Social determinants of health is one of the topics that has attracted researchers' attention in recent decades, which is consistent with it, the public health, as one of the influencing factors to quality of life is taken into consideration. The purpose of this study was to examine the impact of social well-being on quality of life among Meshginshahr PNU students with using survey method. In order to, A sample of 330 students of PNU Meshginshahr are selected by stratified sampling. For data collection, the Keyes social health questionnaire and the World Health Organization Quality of Life Questionnaire, with 26-item scale (WHOQOL-BREF) is used. To analyze relationships between variables such as t-test, ANOVA and Pearson correlation coefficient was used. Research findings indicate that, There are a significant positive correlation between social health and quality of life of students (r=0/535, sig=0/000), and social heaith also significantly associated with the four dimensions of quality of life, ie, the dimensions of physical health, mental health, environmental health, social relationships health. Also, the student’s quality of life, on the type of residence had no significant difference, but the quality of life of students by gender, field of study and year of entry is no different. Also, there was no significant relationship between age and quality of life for students.