This paper is to analyze the semantic understanding of structures affecting the quality of life of the residents of Oraman Lahon from the social interpretivism point of view. The scope of research is Oraman Lahon in Kermanshah. This study is qualitative. In order for data production, four methods were used including free observation, participant observation, deep interview, and group discussion. To analyze the data, the interpretational content analysis method in general practice was employed. Overall, the data was coded and analyzed in the form of 81 basic concepts, 8 major concepts, and a core coding, i.e. economic, social, cultural, and political subsystems. The core concept was the quality of life, around which other categories formed. These categories represent structures that affect the quality of life among social actors. Findings indicated that the structures affecting the quality of residents' life are multidimensional and complex, affected by components i.e. time and place, and external and internal factors. Therefore, different individuals perceive its meaning differently. The indicators of life quality in the region of Oraman Lahon are social constructions that focus on people's lives in Oraman area. Yet, it is the residents who can accurately judge and evaluate the changes of their life, and its factors. Another point is that the number of aspects these factors study is not so important. What is crucial is that in order for explaining the factors of the quality of life, the proposed model should have a multidimensional frame, in which it is considered that what people may consider in order to determine the changes of their quality of life.